Skin Inflammation (Dermatitis) and Medical Cannabis
Short answer · 1 minute read
Skin inflammation, called dermatitis in medical language, is the immune system reacting inside the skin: redness, swelling, heat, itch or pain. Research on medical marijuana and cannabinoids for inflamed skin is still at the lab bench. In skin cells and in mice, CBD, CBG and CBN lowered inflammatory signals, but no clinical trial in people with an inflammatory skin disease has confirmed a benefit. Whether any cannabis product makes sense for your skin is a question for a physician who knows your treatment.
Every study on this page is labeled for what it is: cells in a dish, animal skin or people. The full review of the evidence starts at what the research shows.
Why patients across the US can rely on this guide
- Each research number links to the paper it came from, listed at the end of the page.
- Studies are marked by model: human skin cells, mouse skin or volunteers. A cell result is never sold as a patient result.
- Mixed and unhelpful findings stay in view, next to the encouraging ones.
- Checked by physicians licensed in the states where we see patients, all of them online. Who they are.
Itching, burning and flare-ups that keep coming back: what chronic skin inflammation takes from daily life
The itch is usually worst at night. You scratch in your sleep, wake up with raw patches, and the broken skin itches even more the next evening. That loop alone can wear a person down for months. Add burning after a shower, a rash that flares before an important meeting, and sleeves pulled down in July.
Then there is the medicine cabinet. A cream that works for a week, a stronger one your doctor wants you to use sparingly, worries about steroids thinning the skin. Many people start searching for something else at exactly this point.
Itch that wakes you up
Night itch breaks sleep, and short sleep makes the next flare more likely. Scratching damages the skin barrier, which lets irritants in and keeps the cycle going.
Skin you want to hide
Red patches on the face, hands or neck are hard to cover. Many people skip the gym, swimming or dates during a flare, and the stress itself can feed the next one.
Creams that work for a week
Chronic forms come in waves. Relief from a cream can fade once it stops, and the fear of overusing steroids leaves many people undertreated between visits.
Flaring now, on a prescription treatment, after radiation or renewing: where to start
Choose the line that sounds most like you. The card below lists the parts of this guide written for that case.
Your skin is flaring right now
First rule out anything urgent: swelling of the face, fever, pus or a rash that spreads fast. Then look at what may have triggered it and how long a flare like yours usually lasts.
You use a steroid, cyclosporine, methotrexate or a biologic
Here your medicine list matters more than any lab result. Some of these drugs share liver pathways with cannabinoids, and some add to drowsiness.
Your skin reacted to radiation therapy
Radiation dermatitis has its own care plan, set by the radiation oncology team. Nothing goes on treated skin without their approval, cannabis products included.
You are thinking about a CBD cream
Most lab work on skin did test compounds applied to cells or in gels, yet none of it tells you what a store cream contains or does. The base of the cream can irritate inflamed skin on its own.
You already have a medical card
Your signed documents are in your account. Renewal is a fresh evaluation, and the rules for it depend on your state.
What is skin inflammation? Medical term, definition and ICD-10 code
Skin inflammation is the skin’s immune response to something it treats as a threat: an irritant, an allergen, an infection, an injury, radiation or a disease of the immune system itself. Blood vessels widen, fluid and immune cells move in, and the area turns red, swollen, warm, itchy or sore.
The medical term is dermatitis. “Derma” means skin and the ending “-itis” means inflammation, the same ending as in arthritis or tonsillitis. Doctors also say eczema for several of the itchy, scaly forms, and “inflammatory skin disease” for the long-lasting conditions such as psoriasis.
Acute inflammation
Starts quickly after a clear cause, such as a new detergent, poison ivy or a burn, and settles once the cause is removed and the skin heals.
Chronic inflammation
Lasts for months or keeps returning in waves, as in atopic dermatitis or psoriasis. The goal of treatment is control of flares rather than a one-time fix.
Medical term and ICD codes
There is no single ICD-10 code called “skin inflammation.” Diagnosis codes describe a specific condition, so the code depends on which type of dermatitis a clinician records [1].
| Diagnosis | ICD-10-CM | Note |
|---|---|---|
| Dermatitis, unspecified | L30.9 | Used when the type is not recorded; covers “eczema” without more detail [1] |
| Atopic dermatitis, unspecified | L20.9 | The common chronic, itchy form, often starting in childhood [1] |
| Contact dermatitis, unspecified cause | L25.9 | A reaction to something that touched the skin [1] |
| Seborrheic dermatitis, unspecified | L21.9 | Scalp, eyebrows and the sides of the nose [1] |
| Psoriasis, unspecified | L40.9 | An immune disease with thick, scaly plaques [1] |
| Rosacea, unspecified | L71.9 | Facial redness and bumps [1] |
| Urticaria, unspecified | L50.9 | Hives [1] |
| Radiodermatitis, unspecified | L58.9 | Skin reaction to radiation therapy [1] |
| Older ICD-9-CM equivalent | 692.9 (ICD-9) | “Contact dermatitis and other eczema, unspecified cause”; used for care before October 1, 2015 [2] |
The code on your records is chosen by the clinician who examined you. This table helps you read a visit note; it does not tell you which code applies to you.
Quick answers
Is dermatitis the same as skin inflammation?
Yes, in practice. Dermatitis is the medical word for inflammation of the skin. Atopic, contact and seborrheic dermatitis are types of it.
Is skin inflammation a disease?
Not on its own. It is a reaction that many different conditions share, from a one-off allergy to lifelong psoriasis. The underlying cause decides the treatment.
Is dry skin inflammation?
Plain dry skin is not inflamed. When dryness cracks the skin barrier, though, irritants get in and an itchy red rash can follow; doctors call that a form of eczema.
Is eczema skin inflammation?
Yes. Eczema is a group of inflammatory skin conditions, and atopic dermatitis is the most common of them [3].
Is skin inflammation itchy?
Often, but not always. Eczema and hives itch intensely; an infection or a burn tends to hurt more than it itches. In skin cells, a signal called IL-31 is one of the drivers of itch, which is why it shows up in cannabinoid research below.
The main inflammatory skin disorders · Irritation or inflammation?
Inflammatory skin disorders: eczema, psoriasis, contact dermatitis, rosacea and more
Many conditions share the same redness and itch, but they behave differently over time. Knowing the likely name helps you ask the right questions; the diagnosis itself belongs to a clinician.
Where do you see it? Pick an area to narrow the list.
Atopic dermatitis (eczema)
Dry, very itchy patches in the elbow and knee creases, on the hands, neck or face. Often begins in childhood and runs with asthma and hay fever [3].
Does it go away? It can fade with age, but for many adults it returns in flares. Dermatitis and medical cannabis
Contact dermatitis
A rash exactly where something touched: a soap, nickel in a belt buckle, fragrance, poison ivy. Irritant forms sting; allergic forms itch and blister a day or two later.
Does it go away? Usually, once the trigger is found and avoided.
Seborrheic dermatitis
Greasy yellow scale and redness on the scalp, eyebrows, sides of the nose and behind the ears. Dandruff is its mildest form.
Does it go away? It tends to come back, often in winter or under stress, and is kept down with regular treatment.
Psoriasis
Thick, raised plaques with silvery scale on elbows, knees, scalp and lower back. An immune disease that can also affect the joints [4].
Does it go away? It is lifelong, with flares and calm periods. Psoriasis and medical cannabis
Rosacea
Flushing, lasting redness and small bumps across the cheeks and nose, sometimes with burning or gritty eyes. Heat, alcohol and spicy food can set it off.
Does it go away? It is long-term, and treatment controls the redness and bumps.
Inflammatory acne
Red, tender bumps and pus-filled spots on the face, chest and back, beyond simple blackheads. Deep cysts can leave scars.
Does it go away? Often eases after the teens or twenties; adult acne is common in women.
Hives (urticaria)
Raised, itchy welts that move around and fade within a day, often after a food, a drug or an infection. Swollen lips or eyelids can come with them.
Does it go away? Most episodes clear in days or weeks; some last longer and need a specialist.
Perioral dermatitis
Small red bumps around the mouth and nose, sparing a thin border at the lips. Steroid creams on the face can trigger or worsen it.
Does it go away? It usually clears with treatment and with stopping the face cream that caused it.
Nothing in this list matches that area.
Skin irritation vs. skin inflammation: what’s the difference?
Irritation is the skin complaining about something on its surface: a harsh soap, rubbing, sweat, a cold wind. It usually settles within hours to days once the contact stops. Inflammation is a fuller immune response, with redness, swelling, warmth and itch that can outlast the trigger. Repeated irritation is one of the most common routes into irritant contact dermatitis [5].
What it is
Irritation
Surface discomfort from friction, dryness or a chemical.
Inflammation
An immune reaction inside the skin.
Typical signs
Irritation
Stinging, tightness, mild pinkness.
Inflammation
Redness, swelling, heat, itch, pain, sometimes blisters or scale.
How long it lasts
Irritation
Fades soon after the contact stops.
Inflammation
Can last for weeks, or come back in flares.
When to see a doctor
Irritation
If it does not settle after you remove the trigger.
Inflammation
If it spreads, blisters, oozes or keeps returning.
Which of these do you see right now?
Tap the signs that fit. This is a note for your doctor, not a diagnosis, and nothing is stored.
Skin inflammation symptoms: on the face, around the eyes and all over the body
The same process looks different depending on where it happens. Thin skin reddens and swells easily, thick skin on the palms cracks and scales, and folds trap heat and moisture. Pick an area.
Face
Redness, flaking, burning or bumps across the cheeks, nose, chin or hairline. Rosacea, seborrheic dermatitis and perioral dermatitis are the usual suspects, along with reactions to skin care and makeup.
- Stop new products for two weeks and use one plain cleanser and moisturizer.
- Avoid putting a strong steroid cream on the face unless a doctor prescribed it there.
- See a doctor if bumps fill with pus or the redness spreads.
Around the eyes
Eyelid skin is the thinnest on the body and reacts first to eye makeup, nail polish carried on fingertips, contact lens solutions and hay fever. Puffiness, scaling and itch are typical.
- Put nothing on the eyelids without a prescription, including CBD or other cannabis products.
- Pain in the eye, blurred vision or light sensitivity needs a same-day visit.
- Swelling of the lids with trouble breathing is an emergency.
Legs and skin folds
On the lower legs, poor circulation can cause itchy, darkened, swollen skin. In the armpits, groin and under the breasts, heat and moisture invite rash and yeast.
- Keep folds dry and use loose cotton during a flare.
- A hot, red, painful leg that is getting larger can be an infection and needs a doctor the same day.
- Long-lasting leg swelling should be checked for vein or heart causes.
All over the body
A rash that covers large areas can come from a drug reaction, a viral infection, widespread eczema or psoriasis. It is never a case for waiting it out at home.
- Book a same-day visit for a rash that spreads over much of the body.
- Go to emergency care if it comes with fever, peeling, blisters in the mouth or eyes, or feeling very unwell.
- List every new medicine taken in the last eight weeks.
Inflammatory skin disease symptoms
- Redness, which on brown and black skin may look purple, gray or darker brown rather than red.
- Itch, burning or stinging.
- Swelling, warmth or tenderness.
- Dryness, scaling, cracks or thickened skin after months of scratching.
- Blisters, oozing or crusting in acute flares.
- Poor sleep and low mood, which often travel with chronic itch.
What causes skin inflammation, and can inflammation cause skin problems?
Most flares have more than one cause. A weak skin barrier, the genes you were born with and a trigger on the day usually line up together. Finding the trigger is often the cheapest treatment there is.
What came before the flare?
Tap everything that happened in the days before it started; the matching causes open below.
Irritants
Soaps, detergents, solvents, frequent hand washing, sweat and friction strip oils from the skin. Irritant contact dermatitis is the most common type of contact dermatitis and often affects hands [5].
Allergens
Nickel, fragrance, preservatives, hair dye and poison ivy cause allergic contact dermatitis, which usually appears a day or two after contact. A dermatologist can find the culprit with patch testing [5].
A weak skin barrier
In atopic dermatitis the outer layer holds water poorly and lets irritants through. Dry indoor heat, long hot showers and scratching all make the barrier weaker [3].
The immune system and genes
Infection
Bacteria, fungi and viruses inflame the skin directly, and scratched eczema can become infected. Spreading redness, pus, warmth and fever point to infection, which is treated differently and needs a doctor.
Hormones
Many people notice acne, rosacea or eczema flaring in the days before a period, in pregnancy or around menopause. Keeping a diary of flares against your cycle helps your doctor see the pattern.
Medicines
Antibiotics, anti-seizure drugs and many others can cause a drug rash, usually within weeks of starting. Never stop a prescribed medicine on your own; call the prescriber.
Sun and heat
Sunburn is inflammation. Heat and sweat set off rosacea and eczema, and some drugs and plant juices make skin burn faster in sunlight.
How inflammation elsewhere in the body shows on the skin
Yes, inflammation inside the body can cause skin problems. Inflammatory bowel disease, lupus and other immune conditions often have skin signs, and psoriasis is linked with inflammation in the joints [4]. Researchers also use the word “inflammaging” for the low-level inflammation that builds up with age and dries and thins older skin. When skin flares travel with gut, joint or general symptoms, tell your doctor about all of them together. More on the gut side is on inflammatory bowel disease and medical cannabis.
Skin inflammation after radiotherapy (radiation dermatitis)
Radiation therapy damages fast-dividing cells, and skin cells in the treated area are among them. The result, radiation dermatitis, looks like a sunburn on the treatment field and can go on to peeling, moist patches and soreness [6].
-
During the course
Redness, dryness and itch usually build up gradually over the weeks of treatment, only where the beam passes [6].
-
Toward the end
The skin can darken, peel or become moist and tender, especially in folds such as the armpit or under the breast [6].
-
After treatment ends
Most reactions heal over the following weeks. The treated skin may stay drier and more sensitive to sun for a long time [6].
The radiation oncology team manages it: gentle washing, a moisturizer they approve, loose clothing, sun protection and, when needed, prescription creams or dressings [6]. Many over-the-counter products are asked about before use, because some contain ingredients that irritate treated skin.
How long does skin inflammation last, and does it go away?
It depends on the cause. A reaction to a single trigger usually settles within days to a few weeks once the trigger is gone and the skin barrier heals. Chronic conditions such as atopic dermatitis and psoriasis go quiet and flare again for years, and are controlled rather than finished [3][4].
Which pattern sounds like yours?
A reaction to something. Once you stop the contact and protect the skin, it should look better week by week. If it is still there after two to three weeks, or keeps coming back, the cause may be different from what you think.
Comes and goes for months. That is the typical pattern of eczema, psoriasis and rosacea. Healing time per flare depends on how early treatment starts, how much you scratch and whether triggers are avoided. A plan for the next flare matters more than any single cream.
Signs of infection. Pus, crusting, heat and fever mean an infection may be part of it. Skin infections are treated with the right antimicrobial and can need days to weeks; they need a doctor, not waiting.
Not going away on treatment. Inflammation that does not improve on prescribed treatment deserves a second look: a different diagnosis, an allergy to the cream itself or a need for stronger therapy.
Can skin inflammation be cured?
An acute reaction can go away completely. The chronic inflammatory diseases cannot be cured today, but many people reach long stretches with clear or nearly clear skin on the right plan [3][4]. No study has shown that cannabis shortens a flare or changes the course of any skin disease in people.
Can skin inflammation cause cancer?
Everyday rashes, eczema and contact dermatitis do not turn into cancer. Doctors do watch a few specific situations: wounds or scars that stay inflamed for years, and some long-term immune treatments, where skin checks are part of routine follow-up.
The more practical point runs the other way. Some skin cancers can look like a stubborn patch of dermatitis, which is why a spot that does not behave like the rest of your rash should be seen [7].
- A sore that does not heal within a few weeks.
- A spot that changes in size, shape or color.
- A patch that bleeds, crusts and returns.
- A “rash” in one spot that never responds to the creams that clear the rest.
When should you see a doctor about skin inflammation?
Most mild rashes can be watched for a few days. These signs cannot.
Emergency care now
- Swelling of the face, lips, tongue or eyelids, or trouble breathing or swallowing.
- Eye pain, blurred vision or light sensitivity with a rash near the eye.
- Fever with redness that spreads by the hour.
- Blisters or peeling over large areas, or sores in the mouth or eyes.
See a doctor within days
- Pus, crusting or a hot, painful swelling.
- A rash covering a large area of the body.
- Inflammation on skin treated with radiation.
- No improvement after one to two weeks on treatment.
- Itch that keeps you from sleeping night after night.
Cannabis products do not replace this kind of check. If a skin problem worries you, a physician who can see it comes first.
How to treat and reduce skin inflammation: creams, ointments and the best treatment
The best treatment is the one matched to the diagnosis. A cream that clears contact dermatitis can do nothing for an infection, and a steroid that calms eczema can worsen rosacea on the face. Treatment usually climbs a ladder: daily skin care first, prescription creams next, pills, injections or light therapy for severe or widespread disease [8].
| Treatment | What it is for | Worth knowing |
|---|---|---|
| Moisturizers (emollients) | Repair the skin barrier in eczema and dry, irritated skin | Used every day, not only during flares; fragrance-free is safer [8] |
| Topical corticosteroids | Calm a flare of eczema, contact dermatitis or psoriasis | Strength is chosen by body area; weaker ones on the face and folds [8] |
| Calcineurin inhibitor creams | Steroid-free option for eczema, including the face and eyelids | Can sting for the first days [8] |
| Antihistamines | Hives and itch; sedating ones are sometimes used at night | Sedating types add to drowsiness from THC [9] |
| Antibiotics or antifungals | Infection, or infected eczema | Cream or pill depending on how deep and wide it is |
| Phototherapy | Widespread eczema or psoriasis that creams do not control | Several sessions a week in a clinic, for weeks [8] |
| Biologics | Moderate to severe atopic dermatitis or psoriasis | Injections that block a specific immune signal [8][4] |
| JAK inhibitors and other immune pills | Severe disease; includes older drugs such as cyclosporine and methotrexate | Need blood tests and regular follow-up [10][11] |
No treatments match this filter.
Ointment, cream, gel or lotion: what’s the difference
Ointment
Base
Mostly oil, greasy, few preservatives.
Best for
Very dry, cracked or thick skin; stings least.
Cream
Base
Oil and water mixed, absorbs well.
Best for
Daytime use and larger areas.
Gel
Base
Water thickened with agents such as carbomer, sometimes with alcohol.
Best for
Hairy or oily areas; can sting cracked skin.
Lotion
Base
Thin and watery.
Best for
The scalp and wide areas of mildly dry skin.
Carbomer is a common thickener in gels and is generally well tolerated; if a gel stings or worsens a flare, the alcohol or another ingredient may be the reason. Bring the tube to your dermatologist.
Face and thin skin
Facial skin, eyelids and folds absorb more of whatever you put on them. Strong steroid creams used there for long can thin the skin and cause perioral dermatitis or rosacea-like redness, so doctors prefer mild steroids for short periods or steroid-free creams in those areas [8].
Is medical cannabis worth raising with your dermatologist?
For some people it is a fair question, as long as it sits beside the treatment that works rather than replacing it. The research does not show that cannabis helps skin, so the conversation is usually about the problems around the skin, such as itch that breaks sleep, pain from cracked patches or the stress of constant flares.
It may be worth a conversation if
- Chronic itch keeps you awake despite treatment.
- Cracked or inflamed skin hurts most days.
- Flares are frequent and stress feeds them.
- Your full medicine list can be reviewed at the appointment.
Ask first or wait if
- You are pregnant, trying to be or breastfeeding.
- You take cyclosporine, methotrexate, a JAK inhibitor or several sedating medicines.
- You are under 21.
- You have had psychosis or a substance use disorder.
A licensed physician makes the decision at an appointment. This page cannot, and does not try to.
Is my skin problem one to raise with a physician?
Twelve short questions about your skin, your treatment and your health. You get a plain summary of what your answers point to and what to ask at an appointment; it is not a diagnosis.
12 questions · about a minute · your answers stay in this browser
Why cannabis comes up in skin inflammation: the skin’s endocannabinoid system
Your body makes its own cannabinoid-like messengers, such as anandamide, and has receptors that respond to them. Together they are called the endocannabinoid system, and skin has its own copy of it. Keratinocytes, the cells that make up most of the outer skin, carry these receptors and the enzymes that build and break down the messengers [12]. In mouse skin exposed to an irritating chemical, parts of this system switched on as inflammation developed [13].
-
A trigger hits the skin
An irritant, allergen or bacterial fragment reaches skin cells. Labs imitate this with a bacterial toxin called LPS [14].
-
Cells release alarm signals
Keratinocytes send out cytokines and chemokines, small proteins that call immune cells and cause redness and itch [15].
-
Receptors turn the volume
In dishes, cannabinoids acting on CB2, TRPV1 or PPAR-gamma lowered those signals [16][12].
Which receptors were studied?
Pick a receptor to see what it is and what the lab work found.
CB1
The receptor THC binds most strongly, found in nerves and in skin cells. CBN raised CB1 gene activity in human keratinocytes, yet blocking CB1 did not stop CBN from lowering the signal IL-12, so its effect ran mostly through other routes [12].
CB2
Mostly on immune cells. Beta-caryophyllene, a terpene found in cannabis and black pepper, lowered inflammation in skin cells through CB2; blocking CB2 erased the effect [16]. Mustard-exposed mouse skin also showed more CB2 [13].
TRPV1
The “heat and burn” channel that also reacts to chili. CBN reduced IL-31, a signal tied to itch, through TRPV1 in human keratinocytes; a TRPV1 blocker removed that effect [12].
PPAR-gamma
A receptor inside the cell that switches inflammatory genes up or down. CBD’s anti-inflammatory effect in skin cells depended on it: a PPAR-gamma blocker canceled it [16].
GPR55
A less familiar receptor sometimes called a third cannabinoid receptor. Gels that combined thyme terpenes with CBD and CBG shifted its activity along with CB1, CB2 and PPAR-gamma in lab tests [17].
The signals behind redness and itch
IL-6 and TNF-alpha
IL-8, CXCL8 and CCL20
Chemokines that pull immune cells into the skin. Two new cannabinoids made from CBG, cannabizetol and cannabitwinol, lowered IL-8 release in skin cells [15].
IL-31
Often called the itch cytokine, because it acts on nerve endings in the skin. CBN lowered it through TRPV1 in keratinocytes [12].
IL-36G
A signal raised in psoriasis-type inflammation. It fell in lab models treated with thyme terpenes plus CBD and CBG [17].
What the studies found · How the endocannabinoid system works
What the research shows, from strongest to weakest
In short: there are no randomized trials of cannabis products in people with an inflammatory skin disease. Nearly everything comes from skin cells in dishes and from mouse skin, plus one small test of a CBG serum in volunteers.
A randomized trial, where people are assigned by chance to a treatment or a placebo, can show whether something works. An animal study can show a mechanism in a living body. A cell study shows what a compound does to cells kept in a dish, at concentrations chosen by the researchers. The table puts the skin evidence on those rungs.
| Level | What exists for skin inflammation | What it can and cannot tell you |
|---|---|---|
| Trials in people | No randomized trial in patients. One small test of a CBG serum in 20 volunteers over 15 days, rated low-level evidence [19]. | Could show a real effect on skin; so far there is nothing to judge. |
| Animal and tissue studies | Mouse skin exposed to mustard agents [13]; a thyme and cannabinoid gel tested in preclinical models [17]; isolated mouse skin in a hemp extract study [20]. | Shows a mechanism in living tissue; does not predict a result in patients. |
| Cell studies | Human keratinocytes and immune cells treated with CBD, CBDA, CBG, CBN, rare cannabinoids, terpenes and anandamide [12][16][14][15]. | Explains why scientists are interested. Says nothing about doses, products or safety in people. |
What kinds of studies is this evidence built on?
How to read it: one row per type of study among the papers cited on this page; a longer bar means more papers of that type. The strongest designs come first. Gray bars are animal and cell work, useful for ideas and unable to show whether patients benefit. A row with no bar means there are none.
Show as a table
| Design | Studies |
|---|---|
| Meta-analyses | 0 |
| Randomized trials in patients | 0 |
| Small clinical test in people | 1 |
| Animal and preclinical studies | 2 |
| Cell studies | 8 |
Browse the studies yourself
Each card sums up one paper cited here. The one with a mixed result keeps its label.
CBG made by yeast
Lab assays showed antioxidant and anti-inflammatory activity, and a 15-day test of a 0.1% CBG serum in volunteers reported skin barrier benefits; evidence rated low [19].
Thyme terpenes with CBD and CBG
Terpene fractions of a thyme plant combined with CBD and CBG lowered IL-6, TNF-alpha and IL-36G and were built into a 5% topical gel [17].
Mustard agents and the skin’s cannabinoid system
Blistering chemicals switched on CB1, CB2 and related receptors in mouse skin; an experimental FAAH blocker cut inflammation by 80% [13].
CBN and the itch signal
CBN at a non-toxic 2.5 µM lowered IL-31 through TRPV1 and changed the cells’ own cannabinoid enzymes [12].
Cannabizetol, a new cannabinoid
A compound built from two CBG units lowered IL-8 release and NF-kB activity in skin cells at low concentrations [15].
Anandamide and skin immune cells
The body’s own cannabinoid changed how skin immune cells matured and pushed T cells toward one type of response; not simply calming [21].
CBD and beta-caryophyllene
Each lowered inflammatory signals, CBD through PPAR-gamma and the terpene through CB2, alone and together [16].
CBD in tiny fat carriers
Packing CBD into lipid particles of 160-200 nm protected it from UV breakdown and kept its effect on IL-6 in cells [18].
Rare cannabinoids
CBG, CBC, THCV and CBGA lowered inflammatory signals through the endocannabinoid system and the MAPK pathway [14].
CBDA from hemp seed oil and leaves
Safe for skin cells up to 10 µM, harmful at higher levels, and active against several bacteria in a dish [22].
Industrial hemp water extract
A low-THC hemp extract containing CBD and CBDA eased oxidative stress and inflammation in skin cells and isolated mouse skin [20].
No studies of this type are cited here.
CBD, CBG, CBN, THC and terpenes: why the answer differs by compound
“Cannabis” is not one substance. Cannabis sativa holds more than 500 compounds, around 150 of them phytocannabinoids [15], and each acts on its own set of receptors. A finding for CBD on skin cells is a finding for CBD only, at that concentration, in that dish. It does not carry over to THC, to a full-plant product, or the other way round.
| Compound | What was tested | What came out |
|---|---|---|
| CBD (cannabidiol) | Inflamed human keratinocytes; CBD in lipid carriers; CBD in a terpene gel | Lower inflammatory signals through PPAR-gamma [16]; IL-6 regulated and UV breakdown reduced in carriers [18] |
| CBDA (CBD’s raw acid form) | Keratinocytes and bacteria in a dish | Anti-inflammatory and antibacterial activity; harmful to cells above 10 µM [22] |
| CBG (cannabigerol) | Keratinocytes; a 0.1% serum in 20 volunteers | Lower signals via MAPK [14]; skin barrier benefits in a small, low-level test [19] |
| CBN (cannabinol) | Human keratinocytes at 2.5 µM | Lower IL-31, the itch signal, through TRPV1 [12] |
| CBC, THCV and CBGA | Inflamed keratinocytes at 4-13 µM | Lower inflammatory signals; rarely found in meaningful amounts in products [14] |
| Cannabizetol and cannabitwinol | Newly described compounds built from CBG, on skin cells | Lower IL-8 and NF-kB activity; not in any product you can buy [15] |
| Beta-caryophyllene (a terpene) | Inflamed keratinocytes, alone and with CBD | Lower signals through CB2 [16] |
| Thyme terpenes | Combined with CBD and CBG in a gel | Lower IL-6, TNF-alpha and IL-36G in preclinical tests; thyme is not cannabis [17] |
| Anandamide | Skin immune cells (Langerhans cells) | Mixed: changed how the cells mature and respond [21] |
| THC | Hardly tested on inflamed skin in these studies | No skin result to report; its effects on the brain apply to every form that reaches the blood |
No compounds match this filter.
Lab compounds also differ from what a state program sells. Researchers use purified substances at measured concentrations, sometimes new molecules made in the lab. A dispensary cream or oil is a mixture whose content is printed on a lab-tested label, and none of these products was what the studies tested.
How big were the effects in lab studies, and how to read them
Cell studies report strength as IC50: the concentration of a compound that cuts a signal in half. A lower IC50 means less of the compound was needed. It is measured in micromoles per liter (µM) of liquid around cells in a dish. It is not a dose, and it cannot be turned into milligrams for a person.
How much of each compound halved an inflammatory signal?
How to read it: each dot is one compound in one test. Further left means a smaller amount was needed. The scale is logarithmic, so each step to the right multiplies the amount. Choose the signal.
concentration that halved the signal (IC50), skin cells in a dish
When more stops being better
How to read it: how much the skin cells’ activity dropped as CBDA concentration rose. A longer bar means more harm to the cells. Up to 10 µM no harm was seen [22].
Show as a table
| Compound | Measure | Value |
|---|---|---|
| Cannabizetol | IC50, IL-8 release | 1.46 µM [15] |
| Cannabitwinol | IC50, IL-8 release | 6.39 µM [15] |
| Cannabizetol | IC50, NF-kB activity | 4.95 µM [15] |
| Cannabitwinol | IC50, NF-kB activity | 19.8 µM [15] |
| CBDA | Highest concentration without harm to cells | 10 µM [22] |
| CBDA | Drop in cell activity at 25 / 50 / 100 µM | 40.7% / 57% / 84% [22] |
| CBN | Concentration chosen as non-toxic | 2.5 µM [12] |
All concentrations on this page are amounts in a dish, not doses for people.
Forms of cannabis and inflamed skin: what each form avoids and what stays
Almost all of the skin research put compounds on cells or into gels. None of it tested cannabis that was smoked, vaped or eaten against skin inflammation. Medical cannabis also comes as creams and balms, patches, edibles and capsules, drops under the tongue, sprays and, rarely, suppositories. Each form sidesteps some risks and keeps others. Nothing below recommends a form; that choice belongs to a conversation with a physician.
Which form are you asking about?
Choose one to add its own card. The list of what applies to every form is always shown.
Creams, balms and ointments
Act mainly where they are rubbed in and are the closest match to the lab models, which tested compounds on skin cells and in gels [17]. They still carry a base, fragrance and preservatives that can sting or cause allergic contact dermatitis on broken skin. A small test patch and the ingredient list go to your dermatologist first.
Transdermal patches
Built to carry cannabinoids through the skin into the blood. That makes them a whole-body form: drowsiness, dizziness and drug interactions are the same questions as for anything swallowed. The adhesive itself can irritate sensitive skin.
Edibles, drinks and capsules
No smoke, but the liver handles them before they reach the blood. They start slowly and last for hours, and a second helping taken because “nothing happened yet” is a common cause of feeling far too high. They act on the whole body, not on the rash.
Tinctures, oils and mouth sprays
Drops under the tongue or a spray in the cheek, counted dose by dose. Part of each dose is swallowed. Like edibles, they reach the bloodstream and the brain and share the same interaction questions.
Smoking: joints, blunts, pipes, bongs
Does not target the skin at all. Smoke is a product of burning plant matter and reaches the airways, and THC reaches the brain within minutes. Shared mouthpieces pass germs from person to person.
Vaping and dabbing
Heats instead of burning, yet the hot aerosol still lands in the airways. Concentrates such as wax, shatter and rosin are strong enough that a small amount is a large dose. Nothing here is aimed at the skin.
Prescription cannabinoids
Dronabinol, nabilone and Epidiolex are FDA-approved medicines filled at a pharmacy, not products bought with a medical card. None is approved for a skin condition. Epidiolex’s label lists liver enzyme interactions that matter for some skin drugs [23].
True of every form that reaches the blood
- THC can bring drowsiness, dizziness, anxiety and a racing heart.
- CBD and THC pass through liver enzymes that also clear cyclosporine and other drugs [23][10].
- Drowsiness from cannabis adds to sedating antihistamines taken for itch [9].
- The ratio of THC to CBD matters more than the brand name.
- No driving after use.
All forms as a table
| Form | What it avoids | What it keeps |
|---|---|---|
| Creams and balms | Smoke, swallowing, most effects on the brain | Reactions to the cream base and fragrance; unknown benefit for the rash |
| Transdermal patches | Smoke, swallowing | Effects on the brain, interactions, adhesive irritation |
| Edibles and capsules | Smoke, aerosol, shared devices | Slow onset, the second-helping trap, liver processing, interactions |
| Tinctures and sprays | Smoke, aerosol | Effects on the brain, partly swallowed dose, interactions |
| Smoking | A slow onset | Smoke in the airways, shared devices, every effect of THC |
| Vaping and dabbing | Burning plant matter | Hot aerosol in the airways, strong concentrates, every effect of THC |
| Prescription cannabinoids | Unknown product content | Drowsiness, interactions; not approved for skin conditions |
Is cannabis safe for inflamed skin? Side effects to know
Nobody has measured it yet. The studies on this page were not designed to test safety in people with skin disease, and their authors say a human safety profile is still missing. What is known comes from cannabis use in general, and from one clear lab warning: skin cells were harmed at higher CBDA concentrations [22].
Reactions to the cream
Fragrance, preservatives, alcohol and plant extracts in a topical product can cause stinging or allergic contact dermatitis on already inflamed skin [5].
Drowsiness
Common with THC, and stronger alongside a sedating antihistamine for night itch [9]. Feeling sleepier is not the same as itching less.
Dizziness
Lightheadedness and slowed reactions come with THC in any form that reaches the blood, especially at the start or after a dose change.
Anxiety or a racing heart
THC can raise the heart rate and set off anxiety, which some people notice as more scratching, not less.
The second-helping trap
Edibles take an hour or more to act. A second dose taken too early is a frequent route to an unpleasant, long-lasting high.
Driving
THC slows reaction time, and a medical card gives no permission to drive impaired anywhere in the US. Plan rides before any use.
No entries match this filter.
When to call a doctor right away
- The rash spreads, blisters or oozes after you start any new product.
- Swelling of the face, lips or eyelids, or trouble breathing.
- Chest pain, fainting, or a racing or irregular heartbeat.
- Confusion, panic or hallucinations after use.
- Vomiting that does not stop.
Drug interactions: steroids, methotrexate, cyclosporine, antihistamines and biologics
For anyone on systemic skin treatment, the medicine list matters more than the rash. None of the skin studies cited here tested a drug combination in people, so the entries below come from drug labels and general pharmacology. It is a starting list for the appointment, not a complete one.
What is on your list?
Have the pharmacy printout or the boxes in front of you and tap what applies; the matching entries open below.
Steroid and calcineurin creams no data yet
No study cited here tested a cannabis cream on top of a steroid or tacrolimus cream. Layering products on broken skin raises the chance of irritation, and a new reaction makes it hard to tell which product caused it. Ask before combining.
Steroid pills such as prednisone no data yet
Short steroid courses can already disturb sleep and mood. The physician weighs whether adding THC to that makes sense, and stopping prednisone suddenly is never safe.
Cyclosporine and tacrolimus pills label data
Both are cleared by the liver enzyme CYP3A4, and their blood levels are watched closely because too much harms the kidneys [10]. CBD inhibits liver enzymes in the same family, according to the Epidiolex label [23]. A shift in level is a real possibility, which is why these drugs come up first at the appointment.
Methotrexate label data
Sedating antihistamines such as hydroxyzine or diphenhydramine label data
These are often taken at night for itch and cause drowsiness on their own [9]. THC adds to it, and the combination can leave you groggy the next morning and unsafe to drive.
Biologics and JAK inhibitors no data yet
There are no studies on cannabis alongside these newer drugs in skin disease. Tell both the dermatologist and the evaluating physician everything you take, so neither works blind.
Five or more medicines at once label data
The more drugs share liver pathways, the more one change can shift the others [23]. Bring the full list, including over-the-counter sleep aids, allergy pills and supplements.
Questions for the prescribing doctor
- Does anything I take share liver enzymes with CBD or THC?
- Which blood tests would show a change in my drug levels or liver?
- Which of my medicines already make me drowsy?
- Would a product on the skin raise different questions from one swallowed?
- Who else should know: my dermatologist, my pharmacist, my primary care doctor?
Who should not use cannabis for skin inflammation symptoms
Some groups are left out of cannabinoid studies precisely because the risks are higher, which means there is no evidence of safety for them at all. For the people below, the conversation with a physician either waits or ends with a different plan.
- Pregnancy or breastfeeding. THC reaches the baby, and no skin study included pregnant people.
- Children and teenagers, except under a physician’s direct care; the state rules for minors are strict.
- A history of psychosis, schizophrenia or bipolar disorder; THC can trigger or worsen symptoms. See cannabis and psychosis.
- A current or past substance use disorder.
- A known allergy to cannabis plants or to ingredients in the product, which can show up as hives or contact dermatitis.
- Liver disease, or methotrexate with abnormal liver tests [11].
Some of these reasons are temporary. Pregnancy ends, a liver test can normalize, a medicine change can settle. Others, such as a history of psychosis, usually close the question for good. Ask the physician to say which applies.
Hearing “no” to cannabis is not hearing “no” to help. The same appointment can point you back to treatments for itch, sleep and flares that do have evidence behind them.
What science doesn’t know yet
The gaps here are larger than the findings, and the study authors list most of them themselves.
- There are no clinical trials in people with eczema, psoriasis or dermatitis that test a cannabis product for safety and effect [17][12].
- Nobody has measured how these compounds move through, and act in, a whole living body, or what toxic effects they might have there [15].
- Much of the work used one immortalized skin cell line, HaCaT, which does not behave exactly like skin on a person [16][14].
- Results on Strat-M, an artificial membrane that imitates skin, may not match a cream on human skin [18].
- Skin immune cells were studied only in dishes, and with a mixed result [21].
- Doses for people, how long to use anything, and how cannabinoids compare with standard treatment are all unknown.
That is why a lab result, however clean, does not yet translate into benefit for people.
How to read a headline about CBD and skin
1. Who or what was studied?
Cells, mice or people. A cell result is a reason to run a trial, not a reason to buy a cream.
2. How many people, and for how long?
Twenty volunteers over two weeks cannot show whether a benefit lasts through the next flare.
3. Was there a comparison group?
Eczema and psoriasis improve and worsen on their own. Without a placebo group, a good month may be just that.
4. Which compound, at what concentration?
A purified molecule in a dish is not a store cream, and a store cream is not a dispensary oil.
5. What was actually measured?
A lower IL-8 reading in a dish is not less itch on a person. Look for outcomes you would notice yourself.
How to talk to your doctor about cannabis and skin inflammation
Go in with a realistic goal. Cannabis might be discussed for the itch that steals sleep, for pain from cracked skin or for the stress around flares. It is not expected to clear a rash, and your current treatment stays in place unless the doctor who prescribed it changes it. An appointment goes best when it is about one or two clear problems and a complete medicine list.
Keep a two-week skin diary
- Itch at night: how many times it woke you, on a 0-10 scale.
- Photos of the worst patches every few days, in the same light.
- Every cream, wash and medicine, with the time you used it.
- Possible triggers: new products, heat, stress, your cycle.
- Hours slept and how rested you felt.
What to bring
Tap each item when it is ready. Nothing is saved.
Questions to ask
- Is there anything in my medicine list that rules cannabis out for now?
- THC, CBD or a mix, and why that choice for my problem?
- A form on the skin or one that reaches the blood, and what changes between them?
- What would tell us within a few weeks that it helps, or that it does not?
- Which signs mean stop at once, and whom do I call?
What an evaluation can do
- Review your history, diagnoses and medicines.
- Decide whether your state’s rules and your health make a recommendation appropriate.
- Talk through forms, THC and CBD, and what to watch for.
What it won’t do
- Diagnose a new rash or replace your dermatologist.
- Promise a recommendation before the appointment.
- Change or stop your prescribed treatment.
This guide summarizes published research for education and does not replace a physician’s advice. Cannabis has not been shown to treat any inflammatory skin disease in people.
Is skin inflammation a qualifying condition for a medical marijuana card?
It depends on your state and on the exact words of its list. Each medical cannabis program names its own qualifying conditions, and few of them name a skin condition directly. Many include chronic or severe pain, some include broader wording for debilitating conditions, and some let the physician decide.
Lists change when legislatures and health departments update them. The physician checks your records against the current wording at the appointment, so a diagnosis in writing matters more than a symptom you describe.
Listed by name
Your diagnosis is on the list
The plain case. A visit note naming the condition is what the physician needs.
Related diagnosis
A related condition is listed
Chronic pain, arthritis, insomnia or cancer may appear where skin conditions do not. It has to be diagnosed and in your records.
Not on the list
Neither appears
Your state may not offer a card for this yet. Some programs allow physician discretion, and some accept petitions to add conditions.
What else has a doctor diagnosed?
State programs list diagnoses, not symptoms. Choose anything that is already in your records.
Chronic pain. Listed in many programs under its own name or as severe pain. Painful, cracked skin that lasts for months is something the physician can weigh. See chronic pain and medical cannabis.
Psoriasis. Named in a few programs, and psoriatic arthritis brings joint pain into the picture. See psoriasis and medical cannabis.
Arthritis. Several lists include it. See arthritis and medical cannabis.
Insomnia. Night itch often comes with a recorded sleep disorder, which some programs list. See insomnia and medical cannabis.
Cancer or radiation therapy. Cancer is on most lists, and treatment side effects are often covered. See cancer and medical cannabis.
None. The answer then rests on your state’s wording and the physician’s judgment. Start with your state’s page in the state lookup.
Medical card or buying without one: what a medical card changes
In states with adult-use sales, adults can already buy cannabis. A medical card still changes a handful of things, and each state sets the details.
Taxes
With a medical card
In many states patients skip some or all of the special cannabis tax.
Without a card
The full state and local cannabis tax at the register.
Possession and purchase limits
With a medical card
Often higher, under the state program.
Without a card
The adult-use limit, where adult use is legal at all.
Products and testing
With a medical card
State-licensed, lab-tested products with labeled THC and CBD, sometimes medical-only strengths.
Without a card
Adult-use stores where legal; elsewhere, hemp products with looser checks.
Home cultivation
With a medical card
Allowed for patients in some states, with a plant limit.
Without a card
Allowed in some adult-use states, often with fewer plants.
A physician’s review
With a medical card
A licensed physician looks at your diagnoses and medicines first.
Without a card
No one checks your medicine list.
A card also gives you legal standing as a patient under state law, and your registration stays in a confidential state registry. It does not change federal law.
Medical cannabis rules by state: legal status, possession limits, taxes, home cultivation
Four things differ most between states: whether cannabis is legal for medical use only or for adults as well, how much a patient may buy and keep, whether patients pay less tax, and whether they may grow at home. The current numbers live on each state’s page, where they are kept up to date.
States where our physicians see patients. The state page lists qualifying conditions, possession limits, patient taxes and home-grow rules; where we offer renewal, it is linked too.
Approved: can I go straight to a dispensary?
Not always. In some states the signed recommendation is enough to shop. In states that run a patient registry, you register the recommendation with the program first, pay any state fee and wait for the state to issue your card. Your state’s page says which applies.
Getting your card online: what happens after you click
You never sit in a waiting room. The whole route runs from home, and how it works in detail is on how the medical card works.
-
About 5 minutes
Fill in the form
Choose your state, list your diagnoses and medicines, and upload a visit note if you have one.
-
About 15 minutes
Meet a physician licensed in your state
Just you and the physician, from wherever you are. The start time is agreed with the physician, who can run behind with an earlier patient, so plan a free hour around it.
-
In as little as 15 minutes after the appointment, depending on your state
Receive the recommendation
If the physician finds it appropriate, the signed document appears in your account.
-
Timing set by the state
Register if your state asks
Registry states review the recommendation and issue the card on their own schedule; see your state’s rules.
Who runs the appointment
Across 250 reviews from patients in the states where we are licensed. We do not sort them by score and do not hide the low ones.
- 150,000+patients evaluated – everyone who has been through an appointment with us, in every state where we are licensed
- Since 2017doing only this: online evaluations for medical cannabis programs, and nothing else on the side
Each appointment is with a physician licensed where you live, listed on our doctors page. To move an appointment use your appointments page; for anything else write to support from your account. What happens to the fee if no recommendation is issued is answered in the medical card FAQ.
You see the evaluation fee for your state on screen before paying. Any state registration fee goes to the state, not to us.
Who wrote and reviewed this page, and where the facts come from
The Dr. Weedy editorial team wrote this guide from published studies and official medical and coding sources, and physicians from our medical team who hold licenses in the states we serve checked it. You can read their names and licenses on the doctors page; the review date sits under the buttons at the top.
- Research figures carry the paper they came from, and only papers in the reference list are cited.
- Every study is labeled by model, so cell and mouse results are never presented as patient results.
- Background facts, such as diagnosis codes and standard treatments, link to official sources.
- Safety, interactions and who should not use cannabis have their own sections, and nothing promises an outcome.
Found something outdated or wrong? Use the feedback form at the end of the page.
Skin inflammation and medical cannabis: frequently asked questions
Does CBD cream help skin inflammation?
It has not been shown in people. In skin cells, CBD lowered inflammatory signals through PPAR-gamma [16], but no trial in patients with eczema, psoriasis or dermatitis confirms a benefit. Ask a doctor before using one, especially next to prescription skin treatment.
Can cannabis make skin inflammation worse?
It can. Ingredients in a cream can cause contact dermatitis, some people are allergic to the cannabis plant itself, and in a dish higher CBDA concentrations harmed skin cells [22]. Smoke and vapor do not target skin at all.
Have CBG or CBN been studied for skin inflammation?
How long does skin inflammation last?
A reaction to one trigger usually settles within days to a few weeks after the trigger is removed. Chronic conditions such as eczema and psoriasis come and go for years and are controlled with ongoing treatment.
Can skin inflammation be cured, or does it go away on its own?
Acute reactions often go away on their own once the cause is gone. Chronic inflammatory skin diseases have no cure today, though many people keep long stretches of clear skin with treatment.
Is skin inflammation itchy?
Often. Eczema and hives itch the most, while infections and burns hurt more than they itch. Itch that breaks sleep is worth raising with a doctor on its own.
What is the medical term for skin inflammation?
Dermatitis. Doctors add a word for the type, such as atopic, contact or seborrheic dermatitis, and use “eczema” for several itchy forms.
What is the ICD-10 code for skin inflammation?
There is no single code. Unspecified dermatitis is L30.9, and specific types have their own codes, such as L20.9 for atopic dermatitis [1]. The clinician who examines you picks the code.
What is the difference between skin irritation and skin inflammation?
Irritation is surface discomfort that fades soon after the contact stops. Inflammation is an immune reaction with redness, swelling, heat and itch that can outlast the trigger. See the side-by-side comparison.
Can I get a medical marijuana card for skin inflammation?
It depends on your state. Few lists name skin conditions, but a related diagnosis such as chronic pain may be listed, and some states leave room for the physician’s judgment. How states handle it.
After I’m recommended, can I go straight to a dispensary?
In some states yes; in registry states you first register the recommendation and wait for the state card. Your state’s page in the state lookup says which.
What if I lose my card?
The state program that issued it replaces it, usually through its online portal. Steps for a lost medical card.
Do other states accept my medical card?
Some do, under rules called reciprocity, and many do not. Which states accept out-of-state cards.
What about delta-8 THC or CBD products sold without a card?
Hemp-derived products from stores and websites are checked less strictly than state-program products, and their labels may not match the contents. Delta-8 THC acts much like regular THC, with the same drowsiness and interaction questions.
More research on cannabis and skin inflammation
This page cites a selection of studies. Our research library holds every study we track on cannabis and skin inflammation, from laboratory work to clinical trials, and lets you filter them by cannabinoid, study type and year.
- studies
- 35
- in people
- 17
- clinical trials
- 2
Talk to a licensed physician about your skin symptoms
What may be worth discussing: the itch, pain and broken sleep that come with inflamed skin, with your medicine list on the table.
What the research cannot offer yet: proof that cannabis calms a rash in people, or a reason to drop the treatment you have.
The fee for your state is on screen before you pay, and the physician decides whether a recommendation fits.
Share your experience
References
23 sources
- 1. Centers for Medicare & Medicaid Services. ICD-10-CM code files. 2026.
- 2. Centers for Medicare & Medicaid Services. ICD-9-CM diagnosis and procedure codes: abbreviated and full code titles. 2014.
- 3. National Institute of Arthritis and Musculoskeletal and Skin Diseases. Atopic dermatitis. 2026.
- 4. National Institute of Arthritis and Musculoskeletal and Skin Diseases. Psoriasis. 2026.
- 5. MedlinePlus, National Library of Medicine. Contact dermatitis. 2026.
- 6. National Cancer Institute. Skin and nail changes during cancer treatment. 2026.
- 7. American Academy of Dermatology. How to spot skin cancer. 2026.
- 8. American Academy of Dermatology. Atopic dermatitis: treatment. 2026.
- 9. MedlinePlus, National Library of Medicine. Hydroxyzine. 2026.
- 10. MedlinePlus, National Library of Medicine. Cyclosporine. 2026.
- 11. MedlinePlus, National Library of Medicine. Methotrexate. 2026.
- 12. Cannabinol modulates the endocannabinoid system and shows TRPV1-mediated anti-inflammatory properties in human keratinocytes. DOI: 10.1002/biof.2122 PMID: 39275884
- 13. Mustard vesicants alter expression of the endocannabinoid system in mouse skin. DOI: 10.1016/j.taap.2016.04.014 PMID: 27125198
- 14. Rare Phytocannabinoids Exert Anti-Inflammatory Effects on Human Keratinocytes via the Endocannabinoid System and MAPK Signaling Pathway. DOI: 10.3390/ijms24032721 PMID: 36769042
- 15. Cannabizetol, a Novel Cannabinoid: Chemical Synthesis, Anti-inflammatory Activity and Extraction from Cannabis sativa L. DOI: 10.1021/acs.jnatprod.5c00826 PMID: 40994228
- 16. Anti-Inflammatory Properties of Cannabidiol and Beta-Caryophyllene Alone or Combined in an In Vitro Inflammation Model. DOI: 10.3390/ph17040467 PMID: 38675427
- 17. Valorization of Thyme Combined with Phytocannabinoids as Anti-Inflammatory Agents for Skin Diseases. DOI: 10.3390/pharmaceutics17101291 PMID: 41155929
- 18. Cannabidiol-Loaded Nanostructured Lipid Carriers (NLCs) for Dermal Delivery: Enhancement of Photostability, Cell Viability, and Anti-Inflammatory Activity. DOI: 10.3390/pharmaceutics15020537 PMID: 36839859
- 19. In Vitro and Clinical Evaluation of Cannabigerol (CBG) Produced via Yeast Biosynthesis: A Cannabinoid with a Broad Range of Anti-Inflammatory and Skin Health-Boosting Properties. DOI: 10.3390/molecules27020491 PMID: 35056807
- 20. Metabolomic Profile and Antioxidant/Anti-Inflammatory Effects of Industrial Hemp Water Extract in Fibroblasts, Keratinocytes and Isolated Mouse Skin Specimens. DOI: 10.3390/antiox10010044 PMID: 33401488
- 21. Anandamide modulation of monocyte-derived Langerhans cells: implications for immune homeostasis and skin inflammation. DOI: 10.3389/fimmu.2024.1423776 PMID: 38979427
- 22. Cannabidiolic acid in Hemp Seed Oil Table Spoon and Beyond. DOI: 10.3390/molecules27082566 PMID: 35458762
- 23. U.S. Food and Drug Administration. Epidiolex (cannabidiol) prescribing information. 2018.