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Research library

What science knows about medical cannabis

138,591 studies from OpenAlex, PubMed and Semantic Scholar, mapped to the body and to conditions. 26,482 of them have also been read in depth by our AI research pipeline. Pick an organ, a condition or a cannabinoid and see what has been studied.

138,591
studies
59,339
in people
3,631
clinical trials
171
conditions studied
138,591 studies

Studies by part of the body

Tap an organ to see how many studies looked at it, what they studied and the papers themselves.

84k14k14k9.3k7.9k

Tap an organ

See how many studies looked at it, which conditions and cannabinoids they covered, and read the papers.

How cannabis research grew

59% of these studies came out in the last ten years. 225 have no publication year and are not on the chart.

02.5k5k7.5k10k1960198020002020123456
  1. 1964THC is isolated and identified (Gaoni and Mechoulam)
  2. 1985FDA approves dronabinol (Marinol) for chemotherapy nausea
  3. 1988The brain’s cannabinoid receptor (CB1) is discovered
  4. 1992Anandamide, the body’s own cannabinoid, is found
  5. 1996California becomes the first US state to allow medical cannabis
  6. 2018FDA approves Epidiolex, the first cannabis-derived prescription drug

Studies by condition

Conditions with a Dr. Weedy guide link to it. The rest have studies behind them but no guide from us yet.

Substance Use26,011
Substance-Related Disorders 848 clinical trials in people · 475 reviews
No guide yet
Pain Management12,739
310 clinical trials in people · 266 reviews
No guide yet
Substance-Related Disorders8,693
453 clinical trials in people · 204 reviews
No guide yet
Cancer6,580
132 clinical trials in people · 117 reviews
Read our guide →
Psychosis6,276
130 clinical trials in people · 162 reviews
Read our guide →
Depression5,899
105 clinical trials in people · 88 reviews
Read our guide →
Anxiety5,383
165 clinical trials in people · 100 reviews
Read our guide →
Epilepsy3,608
64 clinical trials in people · 85 reviews
Read our guide →
Chronic Pain2,932
Pain Management 60 clinical trials in people · 111 reviews
Read our guide →
HIV2,497
91 clinical trials in people · 32 reviews
Read our guide →

Other topics researchers study

Not conditions, but often the subject of cannabis research: how people use it, the plant itself, how it acts in the body.

How strong is the evidence?

For doctors and careful readers: what kind of studies stand behind the numbers above, for the filters you chose.

Study design

Stronger designs at the top. Reviews pool earlier studies; trials test cannabis against a control.

92,491 studies are not classified yet: our pipeline has not read them.

Who was studied

Cannabinoids studied

Cannabis and medicines studied

The studies

138,591 studies match. Newest first.

  1. Therapeutic Use of Cannabis and Cannabinoids: A Review.

    JAMA · 2026 · cited 62 times

    Narrative reviewPeople: clinical studiesBrain & mindStomach & gutHeart & blood vessels
  2. Glucagon-like peptide-1 receptor agonists and risk of substance use disorders among US veterans with type 2 diabetes: cohort study.

    BMJ (Clinical research ed.) · 2026 · cited 41 times

    Cohort studyPeople: observationalBrain & mindPancreas & metabolism524,817 participants
  3. Prevalence of Nicotine Pouch Use Among Youth and Adults in Great Britain-Analysis of Cross-Sectional, Nationally Representative Surveys.

    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026 · cited 35 times

    Cross-sectional studyPeople: population studiesBrain & mind12,247 participants
  4. Gastroduodenal Disorders

    Gastroenterology · 2026 · cited 32 times

    Stomach & gutSpine & nerves
  5. The efficacy and safety of cannabinoids for the treatment of mental disorders and substance use disorders: a systematic review and meta-analysis.

    The lancet. Psychiatry · 2026 · cited 31 times

    Meta-analysisPeople: clinical studiesBrain & mind2,477 participants
  6. Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990-2023: a Global Burden of Disease Study.

    Nature medicine · 2026 · cited 25 times

    Narrative reviewPeople: population studiesBrain & mind
  7. Cannabis and Mental Health: A Review.

    JAMA internal medicine · 2026 · cited 22 times

    Narrative reviewPeople: observationalBrain & mind
  8. Guidelines for antenatal and preoperative care in cesarean delivery: Enhanced Recovery After Surgery Society recommendations (part 1)-2025 update.

    American journal of obstetrics and gynecology · 2026 · cited 22 times

    Clinical guidelinePeople: clinical studiesReproductive system
  9. Data Resource Profile: The Japan COVID-19 and Society Internet Survey (JACSIS)

    International Journal of Epidemiology · 2026 · cited 21 times

    Brain & mindImmune system & blood
  10. Psilocybin Outside the Clinic: Public Health Challenges of Increasing Publicity, Accessibility, and Use.

    JAMA psychiatry · 2026 · cited 18 times

    Narrative reviewPeople: observational
  11. Single-cell spatiotemporal dissection of the human maternal–fetal interface

    Nature · 2026 · cited 17 times

    Heart & blood vesselsReproductive system
  12. From Polyphenols to Prodrugs: Bridging the Blood-Brain Barrier with Nanomedicine and Neurotherapeutics.

    International journal of molecular sciences · 2026 · cited 13 times

    Narrative reviewPeople: observationalBrain & mind
  13. Targeting Amyloid Beta Aggregation and Neuroinflammation in Alzheimer's Disease: Advances and Future Directions.

    Cells · 2026 · cited 13 times

    Narrative reviewPeople: observationalBrain & mind
  14. Adolescent Cannabis Use and Risk of Psychotic, Bipolar, Depressive, and Anxiety Disorders

    JAMA Health Forum · 2026 · cited 13 times

    Brain & mind
  15. Acute Effects of Oral Cannabinoids on Sleep and High-Density EEG in Insomnia: A Pilot Randomised Controlled Trial.

    Journal of sleep research · 2026 · cited 12 times

    Crossover trialPeople: clinical studiesBrain & mind20 participants
  16. Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus.

    Nature neuroscience · 2026 · cited 12 times

    Animal studyAnimalsBrain & mind
  17. Dose-dependent effect of acute THC on extinction memory recall and fear renewal: a randomized, double-blind, placebo-controlled study.

    Psychopharmacology · 2026 · cited 11 times

    Randomised controlled trialPeople: clinical studiesBrain & mind115 participants
  18. Update of the statement on safety of cannabidiol as a novel food.

    EFSA journal. European Food Safety Authority · 2026 · cited 11 times

    Systematic reviewLiver
  19. Extract engineering of Cannabis sativa yields novel antibacterial cannabinoids targeting Staphylococcus aureus and methicillin-resistant Staphylococcus aureus.

    Bioorganic chemistry · 2026 · cited 11 times

    People: observationalImmune system & blood
  20. Acute Effects of Cannabis on Alcohol Craving and Consumption: A Randomized Controlled Crossover Trial.

    The American journal of psychiatry · 2026 · cited 11 times

    Crossover trialPeople: clinical studiesBrain & mind138 participants

About this library

The library collects published research on cannabis and cannabinoids from OpenAlex, PubMed and Semantic Scholar. A paper found in several databases is counted once. The library is updated every night. Retracted papers are left out.

Body areas and conditions are matched from each paper's title, keywords and medical subject headings, and from our AI reading of the full paper where we have it. One study can touch several organs. This page summarises research. It is not medical advice: talk to a doctor before using cannabis for a health condition.

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